ื”ืขื“ืคืชื›ื ืขื•ื“ื›ื ื” ืขื‘ื•ืจ ื”ืžืคื’ืฉ ื”ื–ื”. ื›ื“ื™ ืœืฉื ื•ืช ืืช ื”ื’ื“ืจืช ื”ื—ืฉื‘ื•ืŸ ืœืฆืžื™ืชื•ืช, ืขื‘ืจื• ืืœ
ืœื”ื–ื›ื™ืจื›ื, ื ื™ืชืŸ ืœืขื“ื›ืŸ ืืช ื”ืžื“ื™ื ื” ืื• ื”ืฉืคื” ื”ืžื•ืขื“ืคื•ืช ืขืœื™ื›ื ื‘ื›ืœ ืขืช ื‘
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ืžื”ื• ืคืกื•ืจื™ืื–ื™ืก (ืกืคื—ืช)?

ืคืกื•ืจื™ืื–ื™ืก ื”ื™ื ืžื—ืœืช ืขื•ืจ ื”ื ื—ืฉื‘ืช ืœืžื—ืœื” ืื•ื˜ื•-ืื™ืžื•ื ื™ืช. ื”ื™ื ื’ื•ืจืžืช ืœื”ื•ืคืขืช ืจื‘ื“ื™ื ืงืฉืงืฉื™ื™ื ืžื•ืจืžื™ื ื‘ืขื•ืจ ืขื ื‘ืกื™ืก ืื“ื•ื ื•ืขื‘ื” ื”ืžืœื•ื•ื™ื ื‘ื’ืจื“, ื‘ื”ื ืงืฉื” ืžืื•ื“ ืœื˜ืคืœ. ื”ืจื‘ื“ื™ื ื”ืœืœื• ื ื•ืฆืจื™ื ืžืคื ื™ ืฉืขืงื‘ ื”ื“ืœืงืช ื”ืžืขืจื›ืชื™ืช ืชืื™ ื”ืขื•ืจ ืžืชืจื‘ื™ื ื‘ืงืฆื‘ ื’ื‘ื•ื” ืคื™ ืขืฉืจื” ืžื”ืžืฆื•ืคื”. ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก ืžื•ืคื™ืขื™ื ืœืจื•ื‘ ืขืœ ื”ืžืจืคืงื™ื, ื”ื‘ืจื›ื™ื™ื, ื”ืงืจืงืคืช ื•ื”ื’ื•, ืื‘ืœ ื”ื ื™ื›ื•ืœื™ื ืœื”ื•ืคื™ืข ื‘ื›ืœ ืžืงื•ื ืขืœ ืคื ื™ ืฉื˜ื— ื”ืขื•ืจ. ื’ื ืกื˜ืจืก, ืืœื›ื•ื”ื•ืœ, ืขื™ืฉื•ืŸ, ืžื–ื’ ืื•ื•ื™ืจ ืงืจ ื•ื™ื‘ืฉ ื•ืคืฆื™ืขืช ื”ืขื•ืจ ืื• ื–ื™ื”ื•ื ื‘ืขื•ืจ ื™ื›ื•ืœื™ื ืœืฉืžืฉ ื›ื˜ืจื™ื’ืจื™ื ืœืคืกื•ืจื™ืื–ื™ืก.

ื ื™ืชืŸ ืœื”ืงืœ ืขืœ ื”ืชืœืงื—ื•ื™ื•ืช ืฉืœ ืคืกื•ืจื™ืื–ื™ืก ื‘ืืžืฆืขื•ืช ื’ื™ืฉื•ืช ื˜ื‘ืขื™ื•ืช, ืœืืจื™ื›ื•ืช ื™ืžื™ื ื•ืœื‘ืจื™ืื•ืช ื”ืขื•ืจ ืฉืœื›ื.

1. ืขื ื‘ื™ ืื•ืจื’ื•ืŸ (ื‘ืจื‘ืจื™ืŸ)

 ืขื ื‘ื™ ืื•ืจื’ื•ืŸ (ื”ืฉื ื”ืœื˜ื™ื ื™: Mahonia aquifolium) ื”ื ืฆืžื— ื”ืžืชืื™ื ืœืฉื™ืžื•ืฉ ื›ืžืจื›ื™ื‘ ืฉืœ ืงืจื ืขื•ืจ ืœื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก ืงืœ ืขื“ ื‘ื™ื ื•ื ื™. ื–ื• ื‘ื—ื™ืจื” ืคื•ืคื•ืœืจื™ืช ื‘ืงืจื‘ ืื ืฉื™ื ื”ืžืขื•ื ื™ื™ื ื™ื ื‘ื˜ื™ืคื•ืœื™ื ื˜ื‘ืขื™ื™ื ืœื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก. ืœืขื ื‘ื™ ืื•ืจื’ื•ืŸ, ืฆืžื— ื”ื™ื“ื•ืข ื’ื ื‘ืฉืžื•ืช ื‘ืจื‘ืจื™ืŸ ืื• ื‘ืจื‘ืจื™ืช, ื™ืฉ ืกื’ื•ืœื•ืช ื ื•ื’ื“ื•ืช ื“ืœืงืช ื”ืžืคื—ื™ืชื•ืช ืืช ื”ืื•ื“ื ืฉืœ ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก. ื‘ื™ื™ืฆื•ืจ ื”ืงืจื ืœืžืจื™ื—ื” ื—ื™ืฆื•ื ื™ืช ืžืฉืชืžืฉื™ื ื‘ืขืœื™ื ื•ื‘ื’ื‘ืขื•ืœื™ื ืฉืœ ื”ืฆืžื—. ืžืจื™ื—ืช ืงืจื ื›ื–ื” ืขืœ ื”ื ื’ืขื™ื ื™ื›ื•ืœื” ืœื’ืจื•ื ืœืชื—ื•ืฉืช ืฆืจื™ื‘ื” ืงืœื”.

ื‘ื ื™ืกื•ื™ ืงืœื™ื ื™ ืฉื‘ื“ืง ืฉื™ืžื•ืฉ ื‘ืขื ื‘ื™ ืื•ืจื’ื•ืŸ ื›ื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก 84% ืžื”ืžื˜ื•ืคืœื™ื ื“ื™ื•ื•ื—ื• ืขืœ ืชื’ื•ื‘ื” ื˜ื•ื‘ื” ืขื“ ืžืฆื•ื™ื ืช ืœืงืจื. 63% ืžื”ืžื˜ื•ืคืœื™ื ื“ื™ื•ื•ื—ื• ื›ื™ ื”ืงืจื ืขื ืขื ื‘ื™ ืื•ืจื’ื•ืŸ ื”ื™ื” ืฉื•ื•ื” ืขืจืš ืื• ื˜ื•ื‘ ื™ื•ืชืจ ื‘ื”ืฉื•ื•ืื” ืœื˜ื™ืคื•ืœ ื”ืžืงื•ื‘ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก.

ืžื—ืงืจ ืื—ืจ ืขืงื‘ ืื—ืจ ืžื˜ื•ืคืœื™ื ืขื ืคืกื•ืจื™ืื–ื™ืก ื“ื•-ืฆื“ื“ื™ ืงืœ ืขื“ ื‘ื™ื ื•ื ื™ ืฉื˜ื•ืคืœื• ื‘ืงืจื ืขื ืขื ื‘ื™ ืื•ืจื’ื•ืŸ ื‘ืžืฉืš ื—ื•ื“ืฉ ืื—ื“. ื”ืžื˜ื•ืคืœื™ื ื”ื“ื’ื™ืžื• ืฉื™ืคื•ืจ ื‘ืคืกื•ืจื™ืื–ื™ืก ื›ืขื‘ื•ืจ ืฉื‘ื•ืข ืื—ื“ ืฉืœ ื˜ื™ืคื•ืœ, ื›ืืฉืจ ืžืฆื‘ื• ืฉืœ ื”ืฆื“ ืฉื˜ื•ืคืœ ื‘ืงืจื ืขื ืขื ื‘ื™ ืื•ืจื’ื•ืŸ ื”ื™ื” ื˜ื•ื‘ ื™ื•ืชืจ ืžืžืฆื‘ื• ืฉืœ ื”ืฆื“ ืฉื˜ื•ืคืœ ื‘ืงืจื ื‘ื• ื”ืฉืชืžืฉื• ื›ื‘ื™ืงื•ืจืช.

2. ืืœื•ื•ืจื”

ื‘ื–ื›ื•ืช ื”ื”ืฉืคืขื” ื”ืžืฆื ื ืช ื•ื”ืžืจื’ื™ืขื” ืฉืœื”, ืืœื•ื•ืจื” ืžืชืื™ืžื” ืœืžื’ื•ื•ืŸ ืฉื™ืžื•ืฉื™ื ื—ื™ืฆื•ื ื™ื™ื, ื›ื•ืœืœ ื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก. ืœืคื™ ืžืื™ื• ืงืœื™ื ื™ืง, ื ื™ืชืŸ ืœื”ืฉืชืžืฉ ื‘ืงืจื ืœืฉื™ืžื•ืฉ ื—ื™ืฆื•ื ื™ ื”ืžื›ื™ืœ ืœืคื—ื•ืช 0.5% ืืœื•ื•ืจื” ืœื˜ื™ืคื•ืœ ื‘ื”ืชืœืงื—ื•ื™ื•ืช ืคืกื•ืจื™ืื–ื™ืก ืงืœื•ืช. ื™ืฉ ืœืžืจื•ื— ืืช ื”ืงืจื ืคืขื ืื—ืช ืขื“ ืฉืœื•ืฉ ืคืขืžื™ื ื‘ื™ื•ื ื‘ืžืฉืš ื—ืžื™ืฉื” ื™ืžื™ื ื‘ืจืฆืฃ ื›ื“ื™ ืœื”ืคื—ื™ืช ืืช ื”ื“ืœืงืช ื•ืœืกื™ื™ืข ืœื˜ื™ืคื•ืœ ื‘ื”ืชืœืงื—ื•ืช. ื™ื™ืชื›ืŸ ืฉื™ื™ื“ืจืฉ ืคืกืง ื–ืžืŸ ืžื”ืงืจื ืœืคื ื™ ืกื‘ื‘ ื”ืžืจื™ื—ื” ื›ื“ื™ ืœืžื ื•ืข ื’ื™ืจื•ื™ ืฉืœ ื”ืขื•ืจ.

ืžื—ืงืจ ืงืœื™ื ื™ ืื—ื“ ืขืงื‘ ืื—ืจ ืžื˜ื•ืคืœื™ื ื‘ื’ื™ืœ ื‘ื™ืŸ 18 ืขื“ 50 ืฉื ื” ืขื ืคืกื•ืจื™ืื–ื™ืก ืฉืื•ื‘ื—ืŸ ืœืคื ื™ ื›ืฉืžื•ื ื” ื•ื—ืฆื™ ืฉื ื™ื ื‘ืžืžื•ืฆืข. ื”ืžื˜ื•ืคืœื™ื ื ื‘ื“ืงื• ืžื“ื™ ืฉื‘ื•ืข. ื”ื“ื’ืžืช ื ืกื™ื’ื” ื”ื“ืจื’ืชื™ืช ืฉืœ ื”ื ื’ืขื™ื ืขื ื™ืจื™ื“ื” ื‘ืื•ื“ื ื•ื‘ื ืคื™ื—ื•ืช ื‘ื”ืžืฉืš ื•ื™ืจื™ื“ื” ื‘ื ื™ืงื•ื“ PASI (ืžื“ื“ ืฉื˜ื— ื•ื—ื•ืžืจืช ื”ืคืกื•ืจื™ืื–ื™ืก) ื ื—ืฉื‘ื” ื›ื”ื—ืœืžื”. ื ื™ืงื•ื“ PASI ืžืฉืžืฉ ืœื”ืขืจื›ืช ื”ื—ื•ืžืจื” ืฉืœ ืคืกื•ืจื™ืื–ื™ืก. ืคืกื•ืจื™ืื–ื™ืก ืขื ื ื™ืงื•ื“ ืฉืœ 5-10 ื ื—ืฉื‘ ืœืžื—ืœื” ื‘ื™ื ื•ื ื™ืช, ื•ื ื™ืงื•ื“ ืžืขืœ 10 ืžืขื™ื“ ืขืœ ืžื—ืœื” ืงืฉื”. ื›ืœ ื”ืžื˜ื•ืคืœื™ื ืกื‘ืœื• ืืช ื”ื˜ื™ืคื•ืœ ื”ื™ื˜ื‘, ืœืœื ืชื•ืคืขื•ืช ืœื•ื•ืื™.

ืขื“ ืกื•ืฃ ื”ืžื—ืงืจ ืงืจื ืืœื•ื•ืจื” ื”ื‘ื™ื ืœืจื™ืคื•ื™ ืฉืœ 25/30 ืžื”ืžื˜ื•ืคืœื™ื (83.3%), ืœืขื•ืžืช ืฉื™ืขื•ืจ ืจื™ืคื•ื™ ืฉืœ 2/30 (6.6%) ื‘ืงื‘ื•ืฆืช ื”ืคืœืฆื‘ื•, ืขื ื ืกื™ื’ื” ืžืฉืžืขื•ืชื™ืช ืฉืœ ืจื‘ื“ื™ ื”ืคืกื•ืจื™ืื–ื™ืก (82.8% ืœืขื•ืžืช 7.7% ื‘ืงื‘ื•ืฆืช ื”ืคืœืฆื‘ื•) ื•ื™ืจื™ื“ื” ืžืžื•ืฆืขืช ืฉืœ 2.2 ื‘ื ื™ืงื•ื“ PASI.

ื™ืฉ ืœืืœื•ื•ืจื” ื’ื ืกื’ื•ืœื•ืช ืžืขื›ื‘ื•ืช ื”ื–ื“ืงื ื•ืช, ื•ื–ื” ื™ืชืจื•ืŸ ื ื•ืกืฃ ืฉืœ ืžืจื™ื—ื” ื—ื™ืฆื•ื ื™ืช ืฉืœ ืงืจื ืืœื•ื•ืจื”.

3. ื—ื•ืžืฆื•ืช ืฉื•ืžืŸ ืื•ืžื’ื”-3

ื—ื•ืžืฆื” ืื™ืงื•ึนืกืืคื ื˜ืื ื•ึนืื™ืช (EPA) ื•ื—ื•ืžืฆื” ื“ื•ึนืงื•ึนืกื”ึถืงึฐืกื ื•ึนืื™ืช (DHA) ื”ืŸ ืฉืชื™ ื—ื•ืžืฆื•ืช ืฉื•ืžืŸ ืื•ืžื’ื”-{LRM}3 ืืจื•ื›ื•ืช-ืฉืจืฉืจืช ื”ืžืฆื•ื™ื•ืช ื‘ืฉืคืข ื‘ื“ื’ื™ื ืฉืžื ื™ื ื›ืžื• ืกืœืžื•ืŸ ื•ืžืงืจืœ, ื›ืžื• ื’ื ื‘ืืฆื•ืช ื™ื. ื”ืฉื•ืžื ื™ื ื”ื‘ืจื™ืื™ื ื”ืœืœื• ื”ื ืฉื•ืžื ื™ื ื‘ืœืชื™ ืจื•ื•ื™ื™ื ืฉืชื•ืจืžื™ื ืœื‘ืจื™ืื•ืช ื”ืœื‘ ืขืœ-ื™ื“ื™ ื”ืคื—ืชืช ืจืžื•ืช ื”ื˜ืจื™ื’ืœื™ืฆืจื™ื“ื™ื ื•ืœื—ืฅ ื”ื“ื ืืฆืœ ื—ืœืง ืžื”ืื ืฉื™ื. ื”ืกื’ื•ืœื•ืช ื ื•ื’ื“ื•ืช ื”ื“ืœืงืช ืฉืœ ื—ื•ืžืฆื•ืช ื”ืฉื•ืžืŸ ืื•ืžื’ื”-3 ืขืฉื•ื™ื•ืช ืœืขื–ื•ืจ ืœืžื˜ื•ืคืœื™ื ืขื ืคืกื•ืจื™ืื–ื™ืก.

ืžื—ืงืจ ืงืœื™ื ื™ ื’ื™ืœื” ื›ื™ ื˜ื™ืคื•ืœ ื‘ืืžืฆืขื•ืช ืชื•ืกืฃ ืขื ื—ื•ืžืฆื•ืช ืฉื•ืžืŸ ืื•ืžื’ื”-3 ืžืฉืœื™ื ืืช ื”ื˜ื™ืคื•ืœ ื”ื—ื™ืฆื•ื ื™ ื‘ืคืกื•ืจื™ืื–ื™ืก ื•ืชื•ืจื ืชืจื•ืžื” ืžืฉืžืขื•ืชื™ืช ืœื”ื•ืจื“ืช ื ื™ืงื•ื“ PASI. ื ืžืฆื ื›ื™ ืชื•ืกืคื™ ืื•ืžื’ื”-{LRM}3 ื”ื‘ื™ืื• ืœืฆืžืฆื•ื ื”ื ื’ืขื™ื ื‘ืงืจืงืคืช ื•ืœื”ืคื—ืชืช ื”ื’ืจื“, ื”ืื•ื“ื, ื”ืงื™ืœื•ืฃ ื•ื”ื ืคื™ื—ื•ืช ื‘ืื–ื•ืจื™ื ืฉื˜ื•ืคืœื•.

4. ื›ื•ืจื›ื•ื

ื›ื•ืจื›ื•ืžื™ืŸ, ื”ืžืจื›ื™ื‘ ื ื•ื’ื“ ื”ื“ืœืงืช ื”ืขื™ืงืจื™ ืฉืžื›ื™ืœ ื”ืชื‘ืœื™ืŸ ื›ื•ืจื›ื•ื ืฉืฆื‘ืขื• ื›ืชื•ื-ื–ื”ื•ื‘, ืžืชืื™ื ืœืžืจื™ื—ื” ื—ื™ืฆื•ื ื™ืช ืœื”ืจื’ืขืช ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก ื‘ืขื•ืจ. ื ื™ืชืŸ ื’ื ืœืงื—ืช ื›ื•ืจื›ื•ื ื“ืจืš ื”ืคื” ืœื”ืคื—ืชืช ื”ื“ืœืงืช ื”ืžืขืจื›ืชื™ืช ืืฆืœ ืžื˜ื•ืคืœื™ื ืขื ืคืกื•ืจื™ืื–ื™ืก. ืžืงื•ืจื• ืฉืœ ื›ื•ืจื›ื•ืžื™ืŸ ื”ื•ื ื‘ื”ื•ื“ื• ื•ื‘ืื™ื ื“ื•ื ื–ื™ื”, ืฉื ื”ืฉืชืžืฉื• ื‘ื• ื‘ืขืช ื”ืขืชื™ืงื” ื‘ืชื•ืจ ืชื‘ืœื™ืŸ ื•ื‘ื•ืฉื. ื”ื•ื ืžืคื—ื™ืช ืืช ื”ื‘ื™ื˜ื•ื™ ืฉืœ ืฆื™ื˜ื•ืงื™ื ื™ื ืžืขื•ื“ื“ื™ ื“ืœืงืช ื•ื’ื•ืจืžื™ ื’ื“ื™ืœื” ื›ืžื• ืื™ื ื˜ืจืœื•ืงื™ืŸ-6 (IL-6) ื•-IL-8 ื‘ืงืจื˜ื™ื ื•ืฆื™ื˜ื™ื ืื ื•ืฉื™ื™ื.

ืœืงืจื˜ื™ื ื•ืฆื™ื˜ื™ื ื™ืฉ ืชืคืงื™ื“ ืคืขื™ืœ ื‘ื”ืชืคืชื—ื•ืช ื•ื‘ืฉื™ืžื•ืจ ืฉืœ ื“ืœืงืช ืคืกื•ืจื™ืื˜ื™ืช ื‘ืขื•ืจ ืขืœ-ื™ื“ื™ ื”ืคืจืฉืช ื›ืžื•ืงื™ื ื™ื ื•ืฆื™ื˜ื•ืงื™ื ื™ื, ืžื” ืฉืžื•ื‘ื™ืœ ืœื”ืžืฉืš ื”ืคืขืœืช ืชืื™ื ื—ื™ืกื•ื ื™ื™ื ื‘ืขื•ืจ. ื–ื”, ื‘ืชื•ืจื•, ืžื’ื‘ื™ืจ ืืช ื”ืชื”ืœื™ืš ื”ื“ืœืงืชื™. ื ื•ืกืฃ ืขืœ ื›ืš, ื™ืฉ ืœืงืจื˜ื™ื ื•ืฆื™ื˜ื™ื ืคืกื•ืจื™ืื˜ื™ื™ื ืงืฆื‘ ืฉื›ืคื•ืœ ืžื•ื’ื‘ืจ, ื›ืœื•ืžืจ ื”ื ืžืชืจื‘ื™ื ื”ืจื‘ื” ื™ื•ืชืจ ืžื”ืจ ืžื”ืจื’ื™ืœ. ื›ื•ืจื›ื•ืžื™ืŸ ื™ื›ื•ืœ ืœืกื™ื™ืข ื‘ื”ืคื—ืชืช ืื•ืชื ื”ืชื”ืœื™ื›ื™ื ื”ื“ืœืงืชื™ื™ื ื‘ืงืจื˜ื™ื ื•ืฆื™ื˜ื™ื, ืกื•ื’ ื”ืชืื™ื ื”ืขื™ืงืจื™ ื‘ืืคื™ื“ืจืžื™ืก, ื”ืฉื›ื‘ื” ื”ืขืœื™ื•ื ื” ื‘ื™ื•ืชืจ ืฉืœ ื”ืขื•ืจ.

ื‘ืคืกื•ืจื™ืื–ื™ืก ืชืื™ื ื—ื™ืกื•ื ื™ื™ื ื ื›ื ืกื™ื ืœืขื•ืจ ื“ืจืš ื›ืœื™ ื”ื“ื ื•ื’ื•ืจืžื™ื ืœืฆืžื™ื—ื” ืžื”ื™ืจื” ืžืื•ื“ ืฉืœ ื”ืืคื™ื“ืจืžื™ืก, ืชื•ืš ืขื™ื›ื•ื‘ ื”ืชื”ืœื™ืš ื”ื˜ื‘ืขื™ ืฉืœ ื”ืฉืœืช ืชืื™ ื”ืขื•ืจ. ื”ืชื•ืฆืื” ื”ื™ื ืขื™ื‘ื•ื™ ื”ืขื•ืจ ื•ื™ืฆื™ืจืช ื ื’ืขื™ื ืงืฉืงืฉื™ื™ื ื”ืžื•ืจื›ื‘ื™ื ืžืชืื™ ืขื•ืจ ืžืชื™ื, ื›ืœื•ืžืจ ืจื‘ื“ื™ ืคืกื•ืจื™ืื–ื™ืก.

ื”ืกื’ื•ืœื•ืช ื ื•ื’ื“ื•ืช ื”ื“ืœืงืช ืจื‘ื•ืช-ื”ืขื•ืฆืžื” ืฉืœ ื›ื•ืจื›ื•ื ื”ื•ืคื›ื•ืช ืื•ืชื• ืœืฆืžื— ืžืฆื•ื™ืŸ ืœืขื™ื›ื•ื‘ ื”ื–ื“ืงื ื•ืช, ื›ื™ ืจื•ื‘ ื”ืžื—ืœื•ืช ื”ื›ืจื•ื ื™ื•ืช ื ื’ืจืžื•ืช ืขืœ-ื™ื“ื™ ื“ืœืงืช ื›ืจื•ื ื™ืช. ื”ืฉืชืžืฉื• ื‘ืงืจืžื™ื ื•ื‘ืชื•ืกืคื™ื ืขื ื›ื•ืจื›ื•ื ืœื‘ืจื™ืื•ืช ื˜ื•ื‘ื” ื•ืœืืจื™ื›ื•ืช ื™ืžื™ื.

5. ืงืคืกืื™ืฆื™ืŸ

ืคืกื•ืจื™ืื–ื™ืก ื’ื•ืจื ืœืฉื™ื ื•ื™ื™ื ื ื™ื›ืจื™ื ื‘ืžืขืจื›ืช ื›ืœื™ ื”ื“ื ื‘ืขื•ืจ, ื•ื™ื™ืชื›ืŸ ืฉื™ืฉ ืœื›ืš ืชืคืงื™ื“ ืžืจื›ื–ื™ ื‘ื”ืชืคืชื—ื•ืช ื”ืžื—ืœื”. ืžื—ืงืจ ืงืœื™ื ื™ ื‘ื—ืŸ ืืช ื”ื”ืฉืคืขื” ืฉืœ ืžืจื™ื—ื” ื—ื™ืฆื•ื ื™ืช ืฉืœ ืงืคืกืื™ืฆื™ืŸ, ื”ื™ื“ื•ืข ื›ืžืขื›ื‘ ืฉืœ ื”ืจื—ื‘ืช ื›ืœื™ ื”ื“ื ื‘ืขื•ืจ, ืขืœ ืคืกื•ืจื™ืื–ื™ืก ื‘ื™ื ื•ื ื™ ืขื“ ื—ืžื•ืจ.

ื”ืžื—ืงืจ ื’ื™ืœื” ืฉื™ืคื•ืจ ื›ืœืœื™ ืžืฉืžืขื•ืชื™ ื™ื•ืชืจ ื‘ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก ืฉื˜ื•ืคืœื• ื‘ืงืคืกืื™ืฆื™ืŸ ื‘ื”ืฉื•ื•ืื” ืœื˜ื™ืคื•ืœ ื‘ืงืจื ืœืœื ืžืจื›ื™ื‘ื™ื ืคืขื™ืœื™ื, ื‘ื• ื”ืฉืชืžืฉื• ืœื‘ื™ืงื•ืจืช. ื ืฆืคืชื” ื™ืจื™ื“ื” ืžืฉืžืขื•ืชื™ืช ื™ื•ืชืจ ื‘ืงื™ืœื•ืฃ ื”ืขื•ืจ ื•ื‘ืื•ื“ื ื‘ืจื‘ื“ื™ื ืฉื˜ื•ืคืœื• ื‘ืงืจื ืขื ืงืคืกืื™ืฆื™ืŸ ืœืฉื™ืžื•ืฉ ื—ื™ืฆื•ื ื™.

ื›ืžืขื˜ ืžื—ืฆื™ืช ืžื”ืžื˜ื•ืคืœื™ื ื”ื‘ื—ื™ื ื• ื‘ืชื—ื•ืฉืช ืฆืจื™ื‘ื”, ืขืงืฆื•ืฅ, ื’ืจื“ ื•ืื•ื“ื ื‘ืขื•ืจ ืœืื—ืจ ื”ืžืจื™ื—ื” ื”ืจืืฉื•ื ื” ืฉืœ ื”ืชื›ืฉื™ืจ ืขื ืงืคืกืื™ืฆื™ืŸ, ืื‘ืœ ื”ืชื•ืคืขื•ืช ื”ืœืœื• ืคื—ืชื• ืื• ื ืขืœืžื• ืœืื—ืจ ืฉื™ืžื•ืฉ ืžืชืžืฉืš ื‘ืงืจื ืขื ืงืคืกืื™ืฆื™ืŸ ืœืฉื™ืžื•ืฉ ื—ื™ืฆื•ื ื™.

6. ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ

ื˜ื‘ื™ืœื” ื‘ืืžื‘ื˜ื™ื™ืช ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ื™ื›ื•ืœื” ืœื”ืจื’ื™ืข ืืช ืจื‘ื“ื™ ื”ืคืกื•ืจื™ืื–ื™ืก ื”ืžื•ื“ืœืงื™ื. ื”ื•ื›ื— ื›ื™ ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ืžืคื—ื™ืชื” ื’ืจื“ ื•ื ืคื™ื—ื•ืช ื‘ืขื•ืจ, ื›ืืฉืจ ื”ืžืจื›ื™ื‘ื™ื ื”ืขื™ืงืจื™ื™ื ืฉืชื•ืจืžื™ื ืœื”ืฉืคืขื” ื”ืžืจื’ื™ืขื” ื”ื–ื• ื”ื ืฉื•ืžื ื™ ืื•ืžื’ื”-3 ื•ืื•ืžื’ื”-6. ืžื—ืงืจื™ื ื”ื“ื’ื™ืžื• ื›ื™ ืื•ื•ื ืื ืชืจืืžื™ื“ื™ื, ื”ืžืจื›ื™ื‘ื™ื ื”ืคืขื™ืœื™ื ืฉืœ ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ, ื™ื›ื•ืœื™ื ืœืขื›ื‘ ืฉื—ืจื•ืจ ืฉืœ ืฆื™ื˜ื•ืงื™ื ื™ื ืžืขื•ื“ื“ื™ ื“ืœืงืช ื•ื”ื™ืกื˜ืžื™ืŸ. ืืœื” ืžื ื’ื ื•ื ื™ื ืžืจื›ื–ื™ื™ื ื‘ืคืชื•ืคื™ื–ื™ื•ืœื•ื’ื™ื” ืฉืœ ืžื—ืœื•ืช ืขื•ืจ ื“ืœืงืชื™ื•ืช ื›ืžื• ืคืกื•ืจื™ืื–ื™ืก.

ื”ืฉืชืžืฉื• ื‘ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ืงื•ืœื•ืื™ื“ื™ืช, ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ื˜ื—ื•ื ื” ื“ืง ืฉืžืชืžื•ืกืกืช ื‘ืžื™ื ืงืจื™ื. ื–ื” ืœื ื™ื’ืจื•ื ืœืกืชื™ืžืช ืคืชื— ื”ื ื™ืงื•ื– ืฉืœ ื”ืืžื‘ื˜ื™ื”. ื”ืชื—ื™ืœื• ืžื—ืฆื™ ื›ื•ืก (ื›-115 ื’ืจ') ืฉืœ ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ืงื•ืœื•ืื™ื“ื™ืช ื•ื”ื’ื“ื™ืœื• ืืช ื”ื›ืžื•ืช ืขื“ 1.5 ื›ื•ืกื•ืช (ื›-340 ื’ืจ') ืœืืžื‘ื˜ื™ื” ืขื ืžื™ื ื—ืžื™ืžื™ื.

ื”ื•ืกืคืช ืฉืžื ื™ื ืืชืจื™ื™ื ืฉืœ ืœื‘ื ื“ืจ, ื‘ื‘ื•ื ื’ ืื• ื‘ืจื’ืžื•ื˜ ืœืžื™ ื”ืืžื‘ื˜ื™ื” ื™ื›ื•ืœื” ืœื”ืขื ื™ืง ื”ืงืœื” ื ื•ืกืคืช. ืื™ืŸ ืœืžืจื•ื— ืฉืžื ื™ื ืืชืจื™ื™ื ื™ืฉื™ืจื•ืช ืขืœ ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก. ื”ื™ื–ื”ืจื• ื›ืฉืืชื ื™ื•ืฆืื™ื ืžื”ืืžื‘ื˜ื™ื”, ืฉื›ืŸ ืฉื™ื‘ื•ืœืช ื”ืฉื•ืขืœ ืขืœื•ืœื” ืœื”ืคื•ืš ืืช ื”ืžื™ื ืœื—ืœืงืœืงื™ื.

ื™ื‘ืฉื• ืืช ื”ืขื•ืจ ื‘ื˜ืคื™ื—ื•ืช ืžื’ื‘ืช ื•ื”ื™ืžื ืขื• ืžืฉืคืฉื•ืฃ ื”ืขื•ืจ ื›ื“ื™ ืœืžื ื•ืข ื’ื™ืจื•ื™. ืœืื—ืจ ื™ื™ื‘ื•ืฉ ื”ืขื•ืจ ืžืจื—ื• ืชื›ืฉื™ืจ ืžืœื—ื— ืขื“ื™ืŸ ื›ืžื• ืฉืžืŸ ืงื•ืงื•ืก ื›ื“ื™ ืœืžื ื•ืข ื‘ืจื™ื—ืช ืœื—ื•ืช. ืฉืžืŸ ื”ืงื•ืงื•ืก ื™ืœื—ื— ืืช ื”ืขื•ืจ ื•ื”ืงืฉืงืฉื™ื ื•ื™ืขื ื™ืง ืกื’ื•ืœื•ืช ื ื•ื’ื“ื•ืช ื“ืœืงืช ื ื•ืกืคื•ืช ืœื”ืจื’ืขืช ื ื’ืขื™ ื”ืคืกื•ืจื™ืื–ื™ืก.

7. ื•ื™ื˜ืžื™ืŸ D

ืžื—ืกื•ืจ ื‘ื•ื•ื™ื˜ืžื™ืŸ {LRM}D ื ืงืฉืจ ืœืคืกื•ืจื™ืื–ื™ืก. ืžื—ืกื•ืจ ื‘ื•ื•ื™ื˜ืžื™ืŸ D ื”ื•ื ืœื ื”ืกื™ื‘ื” ืœืคืกื•ืจื™ืื–ื™ืก, ืื‘ืœ ืจืžื•ืช ื ืžื•ื›ื•ืช ืฉืœื• ื™ื›ื•ืœื•ืช ืœื”ื’ื“ื™ืœ ืืช ื”ืฉื›ื™ื—ื•ืช ืฉืœ ื”ืชืœืงื—ื•ื™ื•ืช ื•ืœืฉื‘ืฉ ืืช ืคืขื™ืœื•ืช ืžืขืจื›ืช ื”ื—ื™ืกื•ืŸ ื•ืืช ื™ื›ื•ืœืชื• ืฉืœ ื”ื’ื•ืฃ ืœืฉืžื•ืจ ืขืœ ื‘ืจื™ืื•ืช ื”ื’ื•ืฃ.

ื ื˜ื™ืœื” ืคื•ืžื™ืช ืฉืœ ื•ื™ื˜ืžื™ืŸ D ืื• ืžืจื™ื—ืชื• ืขืœ ื”ืขื•ืจ ื™ื›ื•ืœื•ืช ืœืกื™ื™ืข ื‘ื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก. ื ื˜ื™ืœื” ืคื•ืžื™ืช ืฉืœ ื•ื™ื˜ืžื™ืŸ D ื‘ืชื•ืจ ืชื•ืกืฃ ืขื•ื–ืจืช ืœื—ื–ืง ืืช ืžืขืจื›ืช ื”ื—ื™ืกื•ืŸ. ืžืื—ืจ ืฉืคืกื•ืจื™ืื–ื™ืก ื”ื™ื ืžื—ืœื” ืื•ื˜ื•-ืื™ืžื•ื ื™ืช, ื–ื” ืขืฉื•ื™ ืœืชืจื•ื ืœื”ืงืœื” ืขืœ ืชืกืžื™ื ื™ ื”ืžื—ืœื”. ืžืจื™ื—ื” ื—ื™ืฆื•ื ื™ืช ืฉืœ ื•ื™ื˜ืžื™ืŸ D ื™ื›ื•ืœื” ืœื”ืื˜ ืืช ืงืฆื‘ ืฉื›ืคื•ืœ ืื• ืฆืžื™ื—ืช ื”ืชืื™ื, ื•ื‘ื›ืš ืœืชืจื•ื ืœืฆืžืฆื•ื ืฉืœ ืจื‘ื“ื™ ืคืกื•ืจื™ืื–ื™ืก.

ื ื™ืชืŸ ืœื”ื’ื“ื™ืœ ืืช ืจืžืช ื•ื™ื˜ืžื™ืŸ D ื‘ื’ื•ืฃ ื’ื ืขืœ-ื™ื“ื™ ื—ืฉื™ืคื” ืœืื•ืจ ื”ืฉืžืฉ, 15 ื“ืงื•ืช ื‘ื™ื•ื ืœืขื•ืจ ื‘ื”ื™ืจ ื•ืขื“ 30 ื“ืงื•ืช ืœืขื•ืจ ื›ื”ื” ื™ื•ืชืจ, ืื• ื‘ืืžืฆืขื•ืช ืžืงื•ืจื•ืช ืชื–ื•ื ืชื™ื™ื ืฉืœ ื•ื™ื˜ืžื™ืŸ D. ื‘ื™ืŸ ื”ืžื–ื•ื ื•ืช ืฉืขืฉื™ืจื™ื ื‘ื•ื•ื™ื˜ืžื™ืŸ D ื“ื’ื™ื ืฉืžื ื™ื ื›ืžื• ื˜ื•ื ื”, ืžืงืจืœ ื•ืกืœืžื•ืŸ ื•ืžื–ื•ื ื•ืช ื”ืžื•ืขืฉืจื™ื ื‘ื•ื•ื™ื˜ืžื™ืŸ D, ื‘ื”ื ืžื•ืฆืจื™ ื—ืœื‘ ืžืกื•ื™ืžื™ื, ืžื™ืฅ ืชืคื•ื–ื™ื, ื—ืœื‘ ืกื•ื™ื” ื•ื“ื’ื ื™ ื‘ื•ืงืจ.

ื•ื™ื˜ืžื™ืŸ D ื”ื•ื ื•ื™ื˜ืžื™ืŸ ื”ืžืกื™ืก ื‘ืฉืžืŸ, ื›ืš ืฉื—ืฉื•ื‘ ืœื”ืงืคื™ื“ ืขืœ ืžืขืงื‘ ืื—ืจ ืจืžื•ืช ื”ื•ื•ื™ื˜ืžื™ืŸ ื‘ืขื–ืจืช ื”ืจื•ืคื ื”ืžื˜ืคืœ ืฉืœื›ื, ื›ื“ื™ ืœืžื ื•ืข ื”ืฆื˜ื‘ืจื•ืช ืœื ื‘ืจื™ืื” ืฉืœื• ื”ืžื›ื•ื ื” ื’ื ืขื•ื“ืฃ ื•ื™ื˜ืžื™ืŸ D ืื• ืจืขื™ืœื•ืช ืฉืœ ื•ื™ื˜ืžื™ืŸ D. ืขื•ื“ืฃ ื•ื™ื˜ืžื™ืŸ D ื™ื›ื•ืœ ืœื’ืจื•ื ืœืขื•ื“ืฃ ืกื™ื“ืŸ ื‘ื“ื, ืžื” ืฉืขืœื•ืœ ืœื”ื•ื‘ื™ืœ ืœื”ืฉืชื ื” ืžืจื•ื‘ื” ื•ืœื—ื•ืœืฉื” ื•ื’ื ืœืคื’ื•ืข ื‘ื›ืœื™ื•ืช. ื‘ื“ืจืš ื›ืœืœ ื–ื” ื ื’ืจื ืจืง ืขืœ-ื™ื“ื™ ืžื™ื ื•ื ื™ื ืžื•ืคืจื–ื™ื ืฉืœ ืชื•ืกืคื™ ื•ื™ื˜ืžื™ืŸ {LRM}D, ื•ืœื ืกื‘ื™ืจ ืฉื•ื•ื™ื˜ืžื™ืŸ D ืžื”ืชื–ื•ื ื” ืื• ืžื—ืฉื™ืคื” ืœืฉืžืฉ ื™ื’ืจืžื• ืœืชื•ืคืขื” ื”ื–ื•.

ื”ืชืžื•ื ื” ื”ื’ื“ื•ืœื”

ื™ืฉ ื’ื™ืฉื•ืช ื˜ื‘ืขื™ื•ืช ืจื‘ื•ืช ืœื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก, ืžืฆืžื—ื™ื ื›ืžื• ื›ื•ืจื›ื•ื ืื• ืขื ื‘ื™ ืื•ืจื’ื•ืŸ ื•ืขื“ ืชื•ืกืคื™ื ื›ืžื• ื•ื™ื˜ืžื™ืŸ {LRM}D ืื• ื—ื•ืžืฆื•ืช ืฉื•ืžืŸ ืื•ืžื’ื”-3. ื”ื”ืฉืคืขื” ื”ืžืจื’ื™ืขื” ืฉืœ ืืœื•ื•ืจื”, ื”ืกื’ื•ืœื•ืช ื ื•ื’ื“ื•ืช ื”ื“ืœืงืช ืฉืœ ืฉื™ื‘ื•ืœืช ืฉื•ืขืœ ื‘ืฉื™ืžื•ืฉ ื—ื™ืฆื•ื ื™ ื•ื”ืขื™ื›ื•ื‘ ืฉืœ ื”ืจื—ื‘ืช ื›ืœื™ ื”ื“ื ื‘ืขื•ืจ ื‘ืืžืฆืขื•ืช ืžืจื™ื—ืช ืงืจื ืขื ืงืคืกืื™ืฆื™ืŸ ื”ืŸ ื—ืœื•ืคื•ืช ื˜ื‘ืขื™ื•ืช ื™ื™ื—ื•ื“ื™ื•ืช ื•ื™ืขื™ืœื•ืช ืœื”ืงืœื” ืขืœ ื ื’ืขื™ ืคืกื•ืจื™ืื–ื™ืก.

ื›ื“ืื™ ืœื ืกื•ืช ื˜ื™ืคื•ืœ ืื—ื“ ื‘ื›ืœ ืคืขื. ื™ื™ืชื›ืŸ ืฉื–ื• ื”ื“ืจืš ื”ื˜ื•ื‘ื” ื‘ื™ื•ืชืจ ืœื“ืขืช ืžื” ื”ื˜ื™ืคื•ืœ ื”ืžืชืื™ื ื‘ื™ื•ืชืจ ืขื‘ื•ืจื›ื. ืœืื—ืจ ืฉื ื™ืกื™ืชื ื›ืœ ืื—ืช ืžื”ืฉื™ื˜ื•ืช ื”ื "ืœ ืœื—ื•ื“, ืชื•ื›ืœื• ืœื”ื—ืœื™ื˜ ืขืœ ืฉื™ืœื•ื‘ ืฉืœ ื”ืฉื™ื˜ื•ืช ืœื”ืŸ ื”ื’ื‘ืชื ื‘ืฆื•ืจื” ื”ื˜ื•ื‘ื” ื‘ื™ื•ืชืจ, ื›ื“ื™ ืœื’ื‘ืฉ ืœืขืฆืžื›ื ืชื›ื ื™ืช ื™ืขื™ืœื” ืœื˜ื™ืคื•ืœ ื‘ืคืกื•ืจื™ืื–ื™ืก. ืœื ืžืฉื ื” ื‘ืื™ื–ื• ื’ื™ืฉื” ื‘ื—ืจืชื, ื”ื˜ื™ืคื•ืœื™ื ื”ื˜ื‘ืขื™ื™ื ื”ืืœื” ืœืคืกื•ืจื™ืื–ื™ืก ืืžื•ืจื™ื ืœื”ืขื ื™ืง ืืช ื”ื”ืงืœื” ื”ืžื™ื•ื—ืœืช ืขื‘ื•ืจ ื”ื ื’ืขื™ื ื”ืคืกื•ืจื™ืื˜ื™ื™ื ื”ืžื’ืจื“ื™ื ื•ื”ืžื•ื“ืœืงื™ื ืฉืœื›ื.

ื”ืคื ื™ื•ืช:

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  2. Barrea L, Savanelli MC, Di Somma C, et al. Vitamin D and its role in psoriasis: an overview of the dermatologist and nutritionist. Rev Endocr Metab Disord.2017;18(2):195-205. doi:10.1007/s11154-017-9411-6
  3. Bernstein JE, Parish LC, Rapaport M, Rosenbaum MM, Roenigk HH Jr. Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris. J Am Acad Dermatol. 1986;15(3):504-507. doi:10.1016/s0190-9622(86)70201-6
  4. Cerio R, Dohil M, Jeanine D, Magina S, Mahรฉ E, Stratigos AJ. Mechanism of action and clinical benefits of colloidal oatmeal for dermatologic practice. J Drugs Dermatol. 2010;9(9):1116-1120.
  5. Gulliver WP, Donsky HJ. A report on three recent clinical trials using Mahonia aquifolium 10% topical cream and a review of the worldwide clinical experience with Mahonia aquifolium for the treatment of plaque psoriasis. Am J Ther. 2005;12(5):398-406. doi:10.1097/01.mjt.0000174350.82270.da
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  7. Syed TA, Ahmad SA, Holt AH, Ahmad SA, Ahmad SH, Afzal M. Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Trop Med Int Health. 1996;1(4):505-509. doi:10.1046/j.1365-3156.1996.d01-91.x

โ€‹ื›ืชื‘ ื•ื™ืชื•ืจ:โ€‹ ืžืจื›ื– ื”ื‘ืจื™ืื•ืช ื”ื–ื” ืœื ื ื•ืขื“ ืœืื‘ื—ืŸ,,, โ€‹ื”ืฆื’ ืขื•ื“